Publications: 2004

Ayyoub, M., Hesdorffer, C.S., Metthez, G., Stevanovic, S., Ritter, G., Chen, Y.-T., Old, L.J., Speiser, D., Cerottini, J.-C. and Valmori, D. 2004. Identification of an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells. J. Immunol. 172:7206-7211.

Ayyoub, M., Hesdorffer, C.S., Montes, M., Merlo, A., Speiser, D., Rimoldi, D., Cerottini, J.-C., Ritter, G., Scanlan, M., Old, L.J., and Valmori, D. 2004. An immunodominant SSX-2-derived epitope recognized by CD4+ T cells in association with HLA-DR. J. Clin. Invest. 113:1225-1233.

Chapatte, L., Servis, C., Valmori, D., Burlet-Schiltz, O., Dayer, J., Monsarrat, B., Romero, P. and Lévy, F. 2004. Final antigenic Melan-A peptides produced directly by the proteasomes are preferentially selected for presentation by HLA-A*0201 in melanoma cells. J. Immunol. 173:6033-6040.

Cobas, M., Wilson, A., Ernst, B., Mancini, S.J.C., MacDonald, H.R., Kemler, R. and Radtke, F. 2004. ?-catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 199:221-229.

Didierlaurent, A., Ferrero, I., Otten, L.A., Dubois, B., Reinhardt, M., Carlsen, H., Blomhoff, R., Akira, S., Kraehenbuhl, J.-P. and Sirard, J.-C. 2004. Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. J. Immunol. 172:6922-6930.

Doucey, M.-A., Scarpellino, L., Zimmer, J., Guillaume, P., Luescher, I.F., Bron, C. and Held, W. 2004. Cis association of Ly49A with MHC class I restricts natural killer cell inhibition. Nature Immunol. 5:328-336.

Gakamsky, D.M., Luescher, I.F. and Pecht, I. 2004. T cell receptor-ligand interactions: a conformational preequilibrium or an induced fit. Proc. Natl. Acad. Sci. USA 101:9063-9066.

Godfrey, D.I., MacDonald, H.R., Kronenberg, M., Smyth, M.J. and Van Kaer, L. 2004. NKT cells: What’s in a name? Nat. Rev. Immunol. 4:231-237.

Gross, D.-A., Graff-Dubois, S., Opolon, P., Cornet, S., Alves, P., Bennaceur-Griscelli, A., Faure, O., Guillaume, P., Firat, H., Chouaib, S., Lemonnier, F.A., Davoust, J., Miconnet, I., Vonderheide, R.H. and Kosmatopoulos, K. 2004. High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy. J. Clin. Invest. 113:425-433.

Hauert, J., Fernandez-Carneado, J., Michielin, O., Mathieu, S., Grell, D., Schapira, M., Spertini, O., Mutter, M., Tuchscherer, G. and Kovacsovics, T. 2004. A template-assembled synthetic protein surface mimetic of the von Willebrand factor A1 domain inhibits botrocetin-induced platelet aggregation. ChemBioChem 5:856-864.

Höflinger, S., Kesavan, K., Fuxa, M., Hutter, C., Heavey, B., Radtke, F. and Busslinger, M. 2004. Analysis of Notch1function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J. Immunol. 173:3935-3944.

Lahav, R., Suvà, M.-L., Rimoldi, D., Patterson, P.H. and Stamenkovic, I. 2004. Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas. Cancer Res. 64:8945-8953.

Lejeune, F.J., Matter, M., Guggisberg, D., Cerottini, J.-P. and Liénard, D. 2004. Prise en charge du mélanome malin cutané au stade de tumeur primaire. Med. Hyg. 2504:2256-2263.

Li, C., Grosdidier, A., Crambert, G., Horisberger, J.-D., Michielin, O. and Geering, K. 2004. Structural and functional interaction sites between Na, K-ATPase and FXYD proteins. J. Biol. Chem. 279:38895-38902.

Liénard, D., Rimoldi, D., Marchand, M., Dietrich, P.-Y., van Baren, N., Geldhof, C., Batard, P., Guillaume, P., Ayyoub, M., Pittet, M.J., Zippelius, A., Fleischhauer, K., Lejeune, F., Cerottini, J.-C., Romero, P. and Speiser, D.E. 2004. Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immun. [serial online] 4:4.
URL:http://www.cancerimmunity.org/v4p4/040404.htm

Meidenbauer, N., Zippelius, A., Pittet, M.J., Laumer, M., Vogl, S., Heymann, J., Rehli, M., Seliger, B., Schwarz, S., Le Gal, F.-A., Dietrich, P.Y., Andreesen, R., Romero, P. and Mackensen, A. 2004. High frequency of functionally active Melan-A-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res. 64:6319-6326.

Meijer, S.L., Dols, A., Hu, H.-M., Chu, Y., Romero, P., Urba, W.J. and Fox, B.A. 2004. Reduced L-selectin (CD62LLow) expression identifies tumor-specific type 1 T cells from lymph nodes draining an autologous tumor cell vaccine. Cell. Immunol. 227:93-102.

Michielin, O., Udry, E., Périard, D., Matzinger, O., Lobrinus, J.A. and Stupp, R. 2004. Irinotecan-induced interstitial pneumonia. Lancet Oncol. 5:322-324.

Montjovent, M.-O., Burri, N., Mark, S., Federici, E., Scaletta, C., Zambelli, P.-Y., Hohlfeld, P., Leyvraz, P.-F., Applegate, L.L. and Pioletti, D.P. 2004. Fetal bone cells for tissue engineering. Bone 35:1323-1333.

Movassagh, M., Spatz, A., Davoust, J., Lebecque, S., Romero, P., Pittet, M., Rimoldi, D., Liénard, D., Gugerli, O., Ferradini, L., Robert, C., Avril, M.-F., Zitvogel, L, and Angevin, E. 2004. Selective accumulation of mature DC-lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 64:2192-2198.

Nagorsen, D., Servis, C., Lévy, N., Provenzano, M., Dudley, M.E., Marincola, F.M. and Lévy, F. 2004. Proteasomal cleavage does not determine immunogenicity of gp100-derived peptides gp100209-217 and gp100209-217T210M. Cancer Immunol. Immunother. 53:817-824.

Radtke, F., Wilson, A. and MacDonald, H.R. 2004. Notch signalling in T-and B-cell development. Curr. Opin. Immunol. 16:174-179.

Radtke, F., Wilson, A., Mancini, S.J.C. and MacDonald, H.R. 2004. Notch regulation of lymphocyte development and function. Nature Immunol. 5:247-253.

Romero, P., Cerottini, J.-C. and Speiser, D.E. 2004. Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination. Cancer Immunol. Immunother. 53:249-255.

Rothenfusser, S., Hornung, V., Ayyoub, M., Britsch, S., Towarowski, A., Krug, A., Sarris, A., Lubenow, N., Speiser, D., Endres, S. and Hartmann, G. 2004. CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro. Blood 103:2162-2169.

Speiser, D.E., Pittet, M.J., Guillaume, P., Lubenow, N., Hoffman, E., Cerottini, J.-C. and Romero, P. 2004. Ex vivo analysis of human antigen-specific CD8+ T-cell responses: Quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring. J. Immunother. 27:298-308.

Tacchini-Cottier, F., Allenbach, C., Otten, L.A. and Radtke F. 2004. Notch1 expression on T cells is not required for CD4+ T helper differentiation. Eur. J. Immunol. 34:1588-1596.

Tardivel, A., Tinel, A., Lens, S., Steiner, Q.-G., Sauberli, E., Wilson, A., Mackay, F., Rolink, A.G., Beermann, F., Tschopp, J. and Schneider, P. 2004. The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur. J. Immunol. 34:509-518.

Teixeiro, E., Daniels, M.A., Hausmann, B., Schrum, A.G., Naeher, D., Luescher, I., Thome, M., Bragado, R. and Palmer, E. 2004. T cell division and death are segregated by mutation of TCR? chain constant domains. Immunity 21:515-526.

Walker, E.B., Haley, D., Miller, W., Floyd, K., Wisner, K.P., Sanjuan, N., Maecker, H., Romero, P., Hu, H.-M., Alvord, W.G., Smith II, J.W., Fox, B.A. and Urba, W.J. 2004. gp100209-2M peptide immunization of human lymphocyte antigen-A2+ stage I-III melanoma patients induces significant increase in antigen-specific effector and long-term memory CD8+ T cells. Clin.Cancer Res.10:668-680.

Wilson, A., Murphy, M.J., Oskarsson, T., Kaloulis, K., Bettess, M.D., Oser, G.M., Pasche, A.-C., Knabenhans, C., MacDonald, H.R. and Trumpp, A. 2004. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev. 18:2747-2763.

Yoon, K., Nery, S., Rutlin, M.L., Radtke, F., Fishell, G. and Gaiano, N. 2004. Fibroblast growth factor receptor signaling promotes radical glial identity and interacts with Notch1 signaling in telencephalic progenitors. J. Neurosci. 24:9497-9506.

Zippelius, A., Batard, P., Rubio-Godoy, V., Bioley, G., Liénard, D., Lejeune, F., Rimoldi, D., Guillaume, P., Meidenbauer, N., Mackensen, A., Rufer, N., Lubenow, N., Speiser, D., Cerottini, J.-C., Romero, P. and Pittet, M.J. 2004. Effector function of human tumor-specific CD8 T cells in melanoma lesions: A state of local functional tolerance. Cancer Res. 64:2865-2873.

Zippelius, A., Bioley, G., Le Gal, F.-A., Rufer, N., Brandes, M., Batard, P., De Smedt, M., Plum, J., Speiser, D.E., Cerottini, J.-C., Dietrich, P.-Y., Romero, P. and Pittet, M.J. 2004. Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J. Immunol. 172:2773-2777.